News
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CSB researchers receive funding for novel research
The American Society for Cell Biology (ASCB) recently announced the formation of Peer Imaging Clusters (PIC) to receive collaborative research grants to pursue novel research projects as part of the PAIR-UP Imaging Science program for Black imaging scientists. Jamaine Davis, PhD Meharry Medical College… Read MoreSep. 20, 2023
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MOE training sessions set for August, September & October
Molecular Operating Environment (MOE) software users can participate in training sessions for small molecule virtual screening, fragment-based drug design and peptide modeling, conformational searching and docking over the next three months. Mauricio Rodriguez, of Chemical Computing Group, will lead the training sessions via Zoom. MOE enables… Read MoreAug. 11, 2023
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Clicking into place with paramagnetic NMR restraints
Kaitlyn Ledwitch, Assistant Research ProfessorJens Meiler, Distinguished Research Professor Nuclear magnetic resonance (NMR) is an incredibly powerful technique for determining protein structure. A complete dataset of chemical shifts (CS) and nuclear Overhauser effects (NOEs) obtained from NMR can be used to determine structural models of a protein of interest. Read MoreJul. 14, 2023
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CSB Spotlight: Yang Lab
John Yang, assistant professor of chemistry, joined the ÐÓ°ÉÔ´´ in the fall of 2020. He forged his path to ÐÓ°ÉÔ´´ via Nankai University in China, UCLA and MIT with research focusing on theoretical and computational chemistry, chemical biology, physical organic chemistry and enzyme catalysis. John… Read MoreJul. 6, 2023
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Jackson named 2023 Chancellor Faculty Fellow
Lauren Jackson, PhDBiological Sciences Congratulations to Lauren Jackson, associate professor of biological sciences, on being selected to the 2023 cohort of Chancellor Faculty Fellows along with twelve other recently tenured faculty. The fellows are composed of highly accomplished teachers and researchers from a wide variety of disciplines and… Read MoreJun. 12, 2023
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Structural plasticity in bacterial flagellar motors
Chemotaxis is the process of moving in response to one environment, and in bacteria, this process is supported largely by flagella. The flagellum is a motility organelle comprised of an elongated filament and various rings, consistent with its role as a rotary motor. One component, the MS-ring, is vital, both… Read MoreJun. 12, 2023
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CSB to co-sponsor Apex Lecture on May 22
The ÐÓ°ÉÔ´´ School of Medicine Basic Sciences is launching the Apex Lecture Series to recognize scientists who are at the forefront of sea-change advances in biomedical discovery. The seminars will connect ÐÓ°ÉÔ´´ campus scientific community with scientists who are pioneering new fields, new… Read MoreMay. 12, 2023
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MOE workshop scheduled for structure-based drug design
In collaboration with the Lee, Mchaourab and Carrasco labs, the CSB is upgrading from four seats of the Molecular Operating Environment (MOE) to a site license that offers unlimited tokens. MOE enables a wide range of molecular… Read MoreMay. 12, 2023
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Structural insights into base excision repair
As the instruction manual of the cell, DNA plays an essential role in development and organism function. Consequently, several mechanisms exist to repair DNA following damage. Oxidants result in structural damage to DNA which are typically repaired via base excision repair (BER). A set of proteins called glycosylases serve to… Read MoreMay. 5, 2023
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Congratulations: Ben Brown & Alican Gulsevin
Ben Brown, PhD Brown receives NIH funding Congratulations to Ben Brown, research assistant professor in the Meiler lab, on his recent NIH award for his project titled Developing a computational platform for induced-fit and chemogenetic drug design. The goal of the project is to integrate AI and physics-based… Read MoreMay. 5, 2023